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anal squamous cell carcinoma develops at the anal squamocolumnar junction and arises from a precancerous lesion called high-grade anal intraepithelial neoplasia (ain-ii, ain-iii). The presence of ain in high-risk groups, especially hiv-positive patients, is an indication for ongoing surveillance by means of high-resolution anoscopy, close followup, topical medications, or other methods. anal and rectal spiradenocylindroma-like basaloid carcinomas have been reported, with cyld gene mutations defined. 41 scattered reports exist of malignant transformation of isolated cylindromas, so this must be a consideration for regular follow-up for patients with cylindromas. Basal cell carcinoma (bcc) is the most common type of malignant cancer found in the world today with a 310 increase in incidence each year. The american cancer society reported that 8 out of 10 patients with skin cancer are suffering from bcc with over 2 million new cases each year. Bcc needs to be detected at the early stages to prevent local destruction causing disabilities to patients. basosquamous (metatypical) carcinoma basal cell carcinoma plus admixed foci indistinguishable from squamous cell carcinoma (not the same as focal squamous differentiation in bcc, which is commonly seen) more aggressive than classic basal cell carcinoma (j am acad dermatol 200960137) may metastasize basal cell nevus syndrome. Carcinoma of the bile ducts is a relatively rare disease with an incidence of 26 cases100. It has a grave prognosis with a one-year survival rate of 53. Cholangiocellular carcinoma (cc) is most common among women and the average age of onset is 50 years. It can present in both intra- and extrahepatic biliary ducts, with the. We describe a case of a 67-year-old man, who underwent chemotherapy and surgery for a right-sided liver tumor with an unusual presentation of metastasis to a lymph node in the left armpit. The patient was asymptomatic at the time of diagnosis but expired 20 months after surgery with epidural, lung, and spine metastasis. invasive squamous cell carcinoma is a type of cancer that occurs in the flat cells that make up the outer layer of skin and the linings of some organs, known as squamous cells. In this case, the word invasive means that the cancerous tumor has penetrated deeply into the skin or organ, as opposed to remaining a surface lesion. For example, in cases of invasive squamous cell carcinoma of the skin. Staging is the process of determining whether cancer has spread and, if so, how far. Squamous cell carcinoma of rectum (rectal squamous cell carcinoma) read more about symptoms,. Tumor immunophenotype was compared to control cases of anal squamous-cell carcinoma and rectal adenocarcinoma,. Basal and squamous cell skin cancer are types of skin cancer that are found on the outer layer of the skin. Squamous cell carcinoma in situ, also called bowen disease,.